Adjunctive Atorvastatin (Lipitor) for MDD?
In a study of patients with major depressive disorder (MDD), adding atorvastatin (Lipitor) to citalopram (Celexa and others) treatment was associated with lower scores on the Hamilton Depression Rating Scale (HDRS).
Antidepressants, Pregnancy, and the Risk of Cardiac Defects
A large cohort study found that commonly prescribed antidepressant medications do not appear to carry cardiac teratogenic effects when used during pregnancy.
Psychotropics and Suicide
FDA warnings that antidepressants and atomoxetine (Strattera) could increase suicidal thinking impacted prescribing patterns and the incidence of psychotropic drug poisonings.
Exposure to SSRIs Does Not Increase Risk of Hepatocellular Carcinoma in Patients with Hepatitis C Infection; Hyperconnectivity Exists Between Brain Networks in Young Unmedicated Remitted Patients with Depression
Antipsychotic Dose Reduction and Adverse Effects
A study of patients with schizophrenia found that decreasing the dose of risperidone (Risperdal and others) or olanzapine (Zyprexa and others) by half did not affect the rate of adverse metabolic effects.
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- J. Rutherford, M.D.