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IN THIS MONTH'S ISSUE:
April 2016

Androgens and Depression
Low serum levels of androgen and estrogen sex steroids might be associated with depression in older men and women.

Metformin for Antipsychotic Weight Gain
A study of South Asian patients provides further evidence for the effectiveness of metformin (Glucophage and others) in combatting antipsychotic-induced weight gain.

Selecting an Antipsychotic for a First Episode of Schizophrenia: Aripiprazole versus Risperidone
Aripiprazole (Abilify and others) is a better choice for a first episode of schizophrenia than risperidone (Risperdal and others) unless akathisia is a concern.

In Brief
Decrease in Cardiovascular Risk Factors Linked to Decline in Rate of Dementia; Coffee and Tea May Have a Dose-Related Protective Effect Against Depression

Transcutaneous VNS
A new study confirms earlier findings that transcutaneous vagus nerve stimulation (tVNS) produces statistically greater reductions in depression than sham stimulation.

Bipolar Maintenance Treatments: Comparing Monotherapies
In a study of maintenance treatments for patients with bipolar disorder, lithium showed greater efficacy than valproate (Depakene and others), olanzapine (Zyprexa and others), and quetiapine (Seroquel and others).

Biological Therapies in Psychiatry Newsletter written by Alan J. Gelenberg, MD
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