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IN THIS MONTH'S ISSUE:
September 2017

Antipsychotics and Cardiovascular Risk
The greater an antipsychotic's likelihood of causing the metabolic abnormalities associated with cardiovascular disease, the more likely it is to be associated with an increased risk of a major cardiovascular event.

Depression, Antidepressants, and Autism
Two studies find no increase in autism in babies exposed to antidepressants during pregnancy.

Second-Step Options for Treating MDD
In patients with depression who respond insufficiently to an adequate trial of an antidepressant, augmentation with an antipsychotic may provide a small benefit in efficacy, counterbalanced by some side effects.

In Brief
Improvements in Diet Associated with Lower All-Cause Mortality; Stressful Conditions Affecting Blacks More Than Whites Are Associated with an Increase in the Risk of Dementia

tDCS for Depression?
In a randomized, controlled trial, transcranial direct-current stimulation (tDCS) was superior to placebo in efficacy but inferior to the selective-serotonin reuptake inhibitor (SSRI) escitalopram (Lexapro and others) in patients with unipolar depression.

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