December 2013

Vortioxetine (Brintellix)
The new antidepressant vortioxetine (Brintellix) is more efficacious than placebo, but whether it has added benefits that will justify its higher cost compared with generic antidepressants has yet to be determined.

Vitamin D and Psychiatric Patients
Patients with chronic mental illness who are deficient in vitamin D should receive nutritional supplements.

Antipsychotics in Dementia: Another Look
Higher doses of antipsychotic drugs seem to increase the risk of death in patients with dementia, but lower doses might not.

In Brief
Both Benzodiazepines and Nonbenzodiazepine Hypnotic Medications Are Associated with an Increased Risk of Fractures

CME 2013
Please be sure to review the Continuing Medical Education (CME) posttest and evaluation for 2013, inserted in this month's issue.

Season's Greetings
Pharmacogenomics may soon provide the key to personalizing medication treatments for each individual patient.

Vortioxetine (Brintellix)

December 2013

On September 30, the US FDA approved vortioxetine (Brintellix), a new medication for the treatment of adults with major depressive disorder (MDD), which is described as a "multimodal antidepressant with a complex mechanism of action."1 Like many antidepressants, vortioxetine inhibits the…

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