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December 2012

CME 2012
Please be sure to review the Continuing Medical Education (CME) registration form and assessment questions for 2012, inserted in this month's issue.

Minocycline for Psychotic Depression?
In a small, open-label trial of patients with psychotic depression, adjunctive minocycline (Minocin) was associated with a large improvement in depressive symptoms.

Looking Back. Looking Ahead.
Dr. Gelenberg's end-of-year editorial and holiday message.

INDEX Volume 35, 2012
2012 Index

NAC, Marijuana, and Adolescents
Preliminary data suggest that treatment with N-acetylcysteine (NAC), in addition to contingency management and counseling, might reduce marijuana use in cannabis-dependent adolescents.

Finasteride and Persistent Psychiatric Side Effects
Depression, suicidal thoughts, and sexual dysfunction associated with finasteride (Propecia, Proscar, and others) may persist long after the medication is discontinued.

Bath Salts and the Serotonin Syndrome
People who abuse "bath salts," especially patients taking serotonergic drugs, are at risk for developing the serotonin syndrome.

In Brief
FDA Announces that Budeprion XL 300 mg Is Not Therapeutically Equivalent to Wellbutrin XL 300 mg; Excess Mortality Due to Alcohol Dependence Higher in Women than in Men

Minocycline for Psychotic Depression?

December 2012

The tetracyclic antibiotic minocycline (Minocin) has anti-inflammatory and neuroprotective properties, as well as antidepressant-like actions in some animal models. Preliminary data also suggest its possible efficacy in treating symptoms of schizophrenia. Miyaoka and collaborators in Japan conducted…

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