November 2012

Pioglitazone (Actos): A New Adjunct for MDD?
Pioglitazone (Actos) shows promise as an adjunctive treatment for depression.

Selenium and Depression
Low dietary selenium intake may increase the risk of depression.

Tablet Splitting
Tablet splitting can be convenient and save money but results vary depending on the patient and the pill.

Depression in CHF Patients: Benefits of Exercise
In a large study of patients with congestive heart failure, aerobic exercise was associated with small decreases in depression, hospitalization, and death.

In Brief
Anxiolytic Effects of Exercise Persist Despite Arousing Stimuli; Children of Parents with Mood Disorders Have Increased Risk of Mood Disorders

Metformin to Counteract Antipsychotic Side Effects
A recent study adds to growing evidence that metformin (Glucophage and others) attenuates antipsychotic-induced side effects such as weight gain, insulin resistance, and amenorrhea.

Selenium and Depression

November 2012

The human body contains roughly 13 to 20 mg of selenium, a micronutrient. Among other functions, selenium attenuates inflammation by suppressing C-reactive protein production. Low levels of brain selenium may be associated with cognitive decline and Alzheimer disease. Inconsistent data suggest that…

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