September 2012

Hot Weather and Mortality Risk in the Mentally Ill
People with mental illness are more likely to die in hot weather than the general population.

Pregabalin (Lyrica): Next-Step Option for Incomplete Response in GAD?
Pregabalin (Lyrica) may help patients with generalized anxiety disorder who respond inadequately to standard treatments.

Varenicline Does Not Increase the Risk of Adverse Cardiovascular Outcomes
A systematic review and meta-analysis found that the risk of adverse cardiovascular outcomes is not increased by treatment with varenicline (Chantix).

Antipsychotics in Young Patients: Comparing Efficacy and Safety
As in the treatment of adults, most second-generation antipsychotics used to treat children are comparable in efficacy but differ in side effects.

In Brief
Antidepressant Treatment Increases Risk of Motor Vehicle Collisions; Chronic Anxiety is Linked to Indicator of Accelerated Aging

Antipsychotics: Quantifying Long-Term Benefits and Risks
After an acute episode of psychosis, the risks and benefits of maintenance treatment with antipsychotic medications should be carefully assessed.

In Brief

September 2012

Orriols and colleagues in France conducted a case-control analysis to estimate the risk of road traffic crashes associated with antidepressant prescriptions (J Clin Psychiatry, in press). The authors gathered data from the national health care insurance database, police reports, and the national…

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