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March 2011

Vilazodone (Viibryd)
Early research suggests the newly approved antidepressant vilazodone (Viibryd) is efficacious and might cause fewer sexual side effects than other antidepressants.

Parkinson Disease and Dementia with Lewy Bodies: A Role for Memantine?
In a double-blind study, memantine (Namenda) was associated with global improvement in dementia but not cognition in patients who had dementia with Lewy bodies.

Omega-3 Fatty Acids in Depression and Pregnancy
A meta-analysis indicates that the ratio of eicosapentaenoic acid (EPA) to docosahexaenoic acid (DHA) in omega-3 polyunsaturated fatty acid supplements determines their antidepressant efficacy, while another study finds DHA supplements during pregnancy ineffective in improving postpartum depression and cognitive scores in newborns.

In Brief
Adult Attention-Deficit/Hyperactivity Disorder (ADHD) May Be Linked to Dementia with Lewy Bodies; Higher Altitude Associated with Increased Suicide Rates

Kava for Anxiety: Is It Worth It?
The modest benefits of kava for the treatment of anxiety may not be worth the risk of hepatotoxicity.

Omega-3 Fatty Acids in Depression and Pregnancy

March 2011

In the United States and elsewhere, fish is the main dietary source of long-chain omega-3 polyunsaturated fatty acids (PUFA), essential nutrients that play important structural and physiological roles in several systems—including central nervous, immune, and cardiovascular.1 Humans…

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