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January 2011

Depression, Inflammation, and Statins
In patients who have had a recent cardiac event, statins are associated with a significant reduction in the risk of depression.

Treating BDD
Although body dysmorphic disorder is difficult to treat, serotonin reuptake inhibitors and cognitive behavioral therapy may improve symptoms.

Measurement-Enhanced Care
A measurement-enhanced care approach to psychiatry, in which symptoms are measured before and during treatment, is seldom used in clinical practice but may become more common in the future.

In Brief
Children with ADHD Have More Chromosomal Structural Abnormalities; Medicare/Medicaid Prescription Plan Switch Associated with Increases in Suicidal Ideation and Behavior

SRIs and Thinning Bone
Highly serotonergic agents may adversely affect bone density.

Stimulants in Dementia
Methylphenidate (Ritalin and others) may provide relief for apathy in patients with dementia but with the risk of adverse cardiovascular and behavioral effects.

In Brief

January 2011

Attention-deficit/hyperactivity disorder (ADHD) is highly heritable, but specific susceptibility genes have not yet been identified. Williams and colleagues analyzed genomes in 410 children with ADHD and over 1100 ethnically matched controls for large (> 500 kb), rare (< 1% population frequency) copy…

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