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IN THIS MONTH'S ISSUE:
September 2017

Antipsychotics and Cardiovascular Risk
The greater an antipsychotic's likelihood of causing the metabolic abnormalities associated with cardiovascular disease, the more likely it is to be associated with an increased risk of a major cardiovascular event.

Depression, Antidepressants, and Autism
Two studies find no increase in autism in babies exposed to antidepressants during pregnancy.

Second-Step Options for Treating MDD
In patients with depression who respond insufficiently to an adequate trial of an antidepressant, augmentation with an antipsychotic may provide a small benefit in efficacy, counterbalanced by some side effects.

In Brief
Improvements in Diet Associated with Lower All-Cause Mortality; Stressful Conditions Affecting Blacks More Than Whites Are Associated with an Increase in the Risk of Dementia

tDCS for Depression?
In a randomized, controlled trial, transcranial direct-current stimulation (tDCS) was superior to placebo in efficacy but inferior to the selective-serotonin reuptake inhibitor (SSRI) escitalopram (Lexapro and others) in patients with unipolar depression.

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Originating at the Massachusetts General Hospital and Harvard Medical School, Biological Therapies in Psychiatry has been a trusted resource for physicians for over 30 years. Described as "influential" by the Atlantic Monthly, this concise, four-page, monthly newsletter provides up-to-date information about the rapidly expanding field of psychotropic medications and other biological treatments for mental disorders.

From his perspective as an editor, teacher, investigator, and clinician, Alan J. Gelenberg, M.D., reviews the widespread literatures of science and clinical practice. Dr. Gelenberg distills the material most relevant for a busy practitioner and presents it each month with a balance of scientific curiosity, healthy skepticism, and clinical experience.

Dr. Gelenberg is Professor and Interim Chair of Psychiatry at Penn State, Hershey. Since 1987, Dr. Gelenberg has been Editor-in-Chief of the Journal of Clinical Psychiatry, and he recently chaired the workgroup that revised the American Psychiatric Association's major depressive disorder guidelines. Dr. Gelenberg has been on the faculty of Harvard Medical School, MIT, and the University of Arizona and has written numerous scientific articles and book chapters on mood disorders, depression, and schizophrenia. He is listed in the Best Doctors in America and America's Top Doctors and received the 1997 Exemplary Psychiatrist Award of the National Alliance for the Mentally Ill.

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