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IN THIS MONTH'S ISSUE:
October 2014

ADHD, Stimulants, and Young Hearts
Stimulant medications, such as methylphenidate (Ritalin and others), are associated with a small increase in the risk of cardiovascular events in children and adolescents, and a slightly greater risk in those with attention-deficit/hyperactivity disorder (ADHD).

Estradiol for Schizophrenia?
In a double-blind, randomized, placebo-controlled trial, women with schizophrenia or schizoaffective disorder had a small but statistically significant improvement in previously treatment-resistant psychotic symptoms when treated with transdermal estradiol.

Rapid Clozapine Titration: Additional Comments
Some patients with schizophrenia may benefit from very gradual (rather than rapid) titration of clozapine (Clozaril and others), especially if they are taking concomitant benzodiazepines.

In Brief
Mindfulness Training Promotes Recovery from Stress in Military Personnel; Compound in Pomegranates May Help Slow Neurodegenerative Disorders

Pregnenolone for Bipolar Depression?
Adjunctive treatment with the neurosteroid pregnenolone may improve depressive symptoms in patients with bipolar disorder.

Allopurinol in Acute Mania?
Preliminary findings indicate benefit from adding allopurinol (Zyloprim and others) to valproate (Depakene and others) for the treatment of acute mania.

Affiliated Links

The Journal of Clinical Psychiatry

The University of Arizona Health Sciences Center- Department of Psychiatry

American Academy of Child and Adolescent Psychiatry

American Association of Suicidology

American Psychiatric Association

American Society for Adolescent Psychiatry

American Society of Addiction Medicine

American Society of Clinical Psychopharmacology

Autism Society of America

Depression and Bipolar Support Alliance (DBSA)

National Alliance for Research on Schizophrenia and Depression (NARSAD)

National Alliance for the Mentally Ill

National Association of Alcoholism and Drug Abuse Counselors

National Institute of Mental Health

National Mental Health Association