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IN THIS MONTH'S ISSUE:
April 2016

Androgens and Depression
Low serum levels of androgen and estrogen sex steroids might be associated with depression in older men and women.

Metformin for Antipsychotic Weight Gain
A study of South Asian patients provides further evidence for the effectiveness of metformin (Glucophage and others) in combatting antipsychotic-induced weight gain.

Selecting an Antipsychotic for a First Episode of Schizophrenia: Aripiprazole versus Risperidone
Aripiprazole (Abilify and others) is a better choice for a first episode of schizophrenia than risperidone (Risperdal and others) unless akathisia is a concern.

In Brief
Decrease in Cardiovascular Risk Factors Linked to Decline in Rate of Dementia; Coffee and Tea May Have a Dose-Related Protective Effect Against Depression

Transcutaneous VNS
A new study confirms earlier findings that transcutaneous vagus nerve stimulation (tVNS) produces statistically greater reductions in depression than sham stimulation.

Bipolar Maintenance Treatments: Comparing Monotherapies
In a study of maintenance treatments for patients with bipolar disorder, lithium showed greater efficacy than valproate (Depakene and others), olanzapine (Zyprexa and others), and quetiapine (Seroquel and others).

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