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IN THIS MONTH'S ISSUE:
July 2015

Generic Olanzapine: Switching from the Brand Name
Despite being associated with a significant drop in blood drug level, switching from brand name olanzapine to a generic formulation did not decrease clinical stability in one study.

Can Anticholinergics Increase Dementia Risk?
Some evidence suggests that, in elderly patients, anticholinergic medications appear to increase the risk of dementia.

The Mediterranean Diet and Cognition
A growing body of evidence suggests that interventions that support cardiovascular health, such as eating a "Mediterranean" type of diet, can also benefit the brain.

Asenapine (Saphris): Once vs Twice Daily
Taking asenapine once rather than twice a day might help offset daytime sleepiness.

In Brief
Patients with Schizophrenia Who Have High Cholesterol Levels Score Better on Cognitive Tests; Supplementation with Folic Acid and Vitamin B Does Not Reduce Depression Risk in Older Women

Suvorexant (Belsomra)
The new hypnotic drug suvorexant, approved for the treatment of insomnia, appears to be similar to earlier agents in terms of effectiveness and side effects, including next-day problems with motor skills, alertness, and cognition.

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