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June 2015

Cannabis and Bipolar Disorder
Patients with bipolar disorder who use cannabis during a mixed or manic episode appear to have poorer function and outcome than those who either stop using it or never have.

Bone Health in Boys: Effects of Risperidone and SSRIs
Boys treated with risperidone (Risperdal and others) and selective serotonin reuptake inhibitors (SSRIs) for prolonged periods experience progressive bone loss and reduced bone mineral density.

Lurasidone for Bipolar Depression
The antipsychotic lurasidone (Latuda) has been approved by the FDA as monotherapy or as an adjunct to lithium or valproate (Depakote and others) for major depressive episodes in adult patients with bipolar I disorder.

In Brief
Measles-Mumps-Rubella Vaccine Does Not Cause Autism Spectrum Disorders in Children at Increased Risk; Clozapine Treatment Does Not Arrest Brain Atrophy and Cortical Thinning in Patients with Schizophrenia

Weight Gain with Antidepressants
In a cross-sectional study of outpatients in Turkey, weight gain occurred in a majority of patients treated with antidepressants.

Does Lithium Lower Dementia Risk?
Prolonged use of lithium in patients with bipolar disorder may lower the rate of developing dementia.

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