IN THIS MONTH'S ISSUE:
April 2017

Anticytokine Treatment for Depression?
Preliminary evidence supports further study of anticytokines for treating depression.

Antidepressants and Fetal Malformations
The overall increase in risk to the fetus from antidepressant exposure during pregnancy is relatively low.

Sleep Medication in Depressed Adolescents
Depressed adolescents who receive trazodone (Desyrel and others) in addition to antidepressants or cognitive-behavioral therapy (CBT) may have worse depression response and increased self-harm.

In Brief
Central Nervous System Polypharmacy Has Increased for Elderly Patients in Outpatient Care Settings; Prolactin-Elevating Antipsychotics Do Not Increase the Risk of Endometrial Cancer

Lithium in Drinking Water: Effects on Adolescents
In a cross-sectional study of junior high students, lithium levels in tap water were inversely correlated with depressive symptoms and interpersonal violence but not with suicidal behaviors.

Diet and Depression: More Data
In a small randomized, controlled trial, the addition of dietary support to psychotherapy or medication treatment for depressed adults was associated with significantly greater improvement in depression scores than the addition of social support.

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