October 2016

Stimulants for ADHD: Tracking Two Adverse Events
For children and adolescents with ADHD, stimulant treatment is associated with an increased risk of cardiovascular events and a decreased risk of anxiety.

Long-Term Effects of Antidepressants on Weight
Bupropion (Wellbutrin and others) may be the most appropriate first-line treatment for depressed patients concerned about long-term weight gain.

Two Antipsychotic Warnings from the FDA
The FDA has issued warnings about a rare but serious skin reaction with olanzapine (Zyprexa and others) and the development of impulse-control problems with aripiprazole (Abilify and others).

Milnacipran and Levomilnacipran
There are few clinically relevant differences between milnacipran (Savella) and its levo enantiomer levomilnacipran (Fetzima).

In Brief
In an Animal Trial, Exercise Increased Production of Brain-Derived Neurotrophic Factor; Exercise Improves Cognitive Function in Patients with Schizophrenia

Anticholinergic Drugs Raise Fracture Risk
Anticholinergic drugs should be avoided in older people for many reasons, including an increased risk of fractures.


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