IN THIS MONTH'S ISSUE:
February 2016

Drugs for Dementia
Current medications for dementia do little to improve cognition or function.

Two New Long-Acting IM Antipsychotics
Aripiprazole lauroxil (Aristada) and a 3-month formulation of paliperidone palmitate (Invega Trinza) have been approved for the treatment of schizophrenia.

Exercise for Late-Life MDD
In a study of older patients with major depressive disorder, both high- and low-intensity exercise added to antidepressant treatment improved remission rates and time to remission.

In Brief
Offspring of Mothers with Polycystic Ovary Syndrome Have Increased Risk of Autism; Androgen Deprivation Therapy Linked to Increased Risk of Alzheimer Disease

A Drug Combination for Agitation in Dementia
In a multicenter trial, the combination of dextromethorphan and quinidine sulfate (Nuedexta) was statistically superior to placebo as a treatment for agitation in patients with Alzheimer disease.

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