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IN THIS MONTH'S ISSUE:
October 2014

ADHD, Stimulants, and Young Hearts
Stimulant medications, such as methylphenidate (Ritalin and others), are associated with a small increase in the risk of cardiovascular events in children and adolescents, and a slightly greater risk in those with attention-deficit/hyperactivity disorder (ADHD).

Estradiol for Schizophrenia?
In a double-blind, randomized, placebo-controlled trial, women with schizophrenia or schizoaffective disorder had a small but statistically significant improvement in previously treatment-resistant psychotic symptoms when treated with transdermal estradiol.

Rapid Clozapine Titration: Additional Comments
Some patients with schizophrenia may benefit from very gradual (rather than rapid) titration of clozapine (Clozaril and others), especially if they are taking concomitant benzodiazepines.

In Brief
Mindfulness Training Promotes Recovery from Stress in Military Personnel; Compound in Pomegranates May Help Slow Neurodegenerative Disorders

Pregnenolone for Bipolar Depression?
Adjunctive treatment with the neurosteroid pregnenolone may improve depressive symptoms in patients with bipolar disorder.

Allopurinol in Acute Mania?
Preliminary findings indicate benefit from adding allopurinol (Zyloprim and others) to valproate (Depakene and others) for the treatment of acute mania.

Continuing Medical Education credits available!

Now sponsored by The CME Institute of Physicians Postgraduate Press, Inc. After reading this volume of Biological Therapies in Psychiatry (BTP), the learner will be able to (1) discuss new psychiatric drugs, including side effects and drug interactions, and (2) describe new information on older medications and new biological treatments.

The CME Institute of Physicians Postgraduate Press, Inc., is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

The CME Institute of Physicians Postgraduate Press, Inc., designates this enduring material for a maximum of 12 AMA PRA Category 1 Credits.™ Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The CME posttest will be provided with the December 2014 issue of BTP. To obtain credit, you must answer 20 of 24 questions correctly and return the answer sheet to the CME Institute of Physicians Postgraduate Press, Inc., by March 31, 2015. The cost for this activity is $30.