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IN THIS ISSUE:
April 2014

Zinc and Depression
Preliminary evidence suggests that zinc deficiency may be associated with depression.

Antidepressant-Induced Sexual Dysfunction: Exercise as an Antidote?
In women experiencing antidepressant-induced sexual dysfunction, exercise appears to improve sexual desire, global sexual function, and orgasm function.

Varenicline in Patients with Depression History
In a study of subjects with past or current depression, varenicline (Chantix) improved cigarette smoking abstinence rates without producing neuropsychiatric adverse effects.

Fluoxetine and the QTc Interval
QTc prolongation can occur in association with fluoxetine (Prozac and others) in patients with a personal or family history of the condition or predisposing risk factors, and in those taking certain other medications.

In Brief
Auditory Training via Computers Improves Cognitive Function in Schizophrenia; Salivary Cortisol Levels Predict Risk for Depression in Young Males

Antipsychotic Strategies in First-Episode Schizophrenia
A recent study found little benefit for high-dose antipsychotic treatment in patients with a first episode of schizophrenia who were nonresponsive to recommended doses.

In Brief

April 2014

A critical target for early intervention in young people with recent-onset schizophrenia is cognitive dysfunction. Cognitive dysfunction is present in the prodrome, worsens with illness onset, and can predict functional outcome. Fisher and colleagues undertook a double-blind, randomized controlled…

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