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IN THIS ISSUE:
April 2014

Zinc and Depression
Preliminary evidence suggests that zinc deficiency may be associated with depression.

Antidepressant-Induced Sexual Dysfunction: Exercise as an Antidote?
In women experiencing antidepressant-induced sexual dysfunction, exercise appears to improve sexual desire, global sexual function, and orgasm function.

Varenicline in Patients with Depression History
In a study of subjects with past or current depression, varenicline (Chantix) improved cigarette smoking abstinence rates without producing neuropsychiatric adverse effects.

Fluoxetine and the QTc Interval
QTc prolongation can occur in association with fluoxetine (Prozac and others) in patients with a personal or family history of the condition or predisposing risk factors, and in those taking certain other medications.

In Brief
Auditory Training via Computers Improves Cognitive Function in Schizophrenia; Salivary Cortisol Levels Predict Risk for Depression in Young Males

Antipsychotic Strategies in First-Episode Schizophrenia
A recent study found little benefit for high-dose antipsychotic treatment in patients with a first episode of schizophrenia who were nonresponsive to recommended doses.

Zinc and Depression

April 2014

In animal research, zinc deficiency has caused behavior that looks like depression. Moreover, exogenous zinc has antidepressant-like activity in experimental animal paradigms: administering zinc supplements to zinc-deficient animals reduces depressive symptoms. Limited clinical evidence suggests zinc…

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