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IN THIS ISSUE:
February 2014

In Brief
Methylphenidate Products May Cause Priapism in Rare Cases; Post-traumatic Stress Disorder Is Associated with an Increased Risk of Weight Gain in Women

Excessive Sweating, Antidepressants, and Terazosin
Augmentation treatment with terazosin (Hytrin) appears to be effective in diminishing antidepressant-induced excessive sweating.

Antipsychotics, Type 2 Diabetes, and Young Patients
In a retrospective cohort study of children, adolescents, and young adults, newly diagnosed cases of type 2 diabetes mellitus were observed about three times as often in antipsychotic users versus nonusers.

Comparing Antipsychotics
A meta-analysis found small differences in efficacy but larger differences in side effects among first- and second-generation antipsychotic medications.

Antidepressants Increase the Risk of Postpartum Hemorrhage
Antidepressants may be associated with a slightly increased risk of postpartum hemorrhage.

Adaptive Treatments for Smokers
The nicotine patch works for about half of people who seek to quit smoking; for the remaining half, other treatments are not as effective.

Antipsychotics, Type 2 Diabetes, and Young Patients

February 2014

Some antipsychotic drugs, particularly several second-generation agents, can cause weight gain, increased blood glucose, and insulin resistance and raise the risk for type 2 diabetes mellitus in adults. Before the introduction of the second generation, antipsychotic agents were prescribed for children…

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