Iloperidone Increases QTc
Coadministration of drugs that inhibit cytochrome P450 2D6 or 3A4 increases the potential for iloperidone (Fanapt) to prolong the QTc interval.
Diabetes and Dyslipidemia: Risks for Adolescents with Mental Illness
A retrospective cohort study found that adolescents with schizophrenia or bipolar disorder had higher rates of both diabetes and dyslipidemia.
Memantine for FTD: A Negative Study
In a double-blind, parallel-group study, memantine (Namenda) produced no benefit greater than placebo for patients with frontotemporal dementia but more frequent cognitive adverse events.
Inappropriate Sexual Behavior in FTD: A Case Report
Aripiprazole (Abilify) reduced inappropriate sexual behavior in an elderly man with frontotemporal dementia.
Age and Dose Play a Role in the Effects of Antidepressants on Fracture Risk; Weight Management Intervention Program Beneficial for Patients with Schizophrenia
Hypertension following SSRI Withdrawal
A woman with depression experienced hypertension when citalopram (Celexa and others) was abruptly discontinued.
Antidepressants, especially serotonergic ones, are associated with an increased risk of fractures (BTP 2013;6:17-18). New reports from Norway and Denmark provide more data on this association. Bakken and colleagues conducted a nationwide prospective cohort study of 906,422 people in Norway…