Vilazodone (Viibryd) Part II
Evidence to date shows no significant benefit of the new selective serotonin reuptake inhibitor (SSRI) vilazodone (Viibryd) over other antidepressants.
Clozapine (Clozaril and others) carries a wide range of side effects, but it is still the most efficacious antipsychotic when patients are inadequately responsive to other agents.
New Cardiac Warning Added to Labeling for Quetiapine (Seroquel); Atomoxetine (Strattera) Does Not Attenuate Weight Gain in Patients with Schizophrenia
No Help from the "Sunshine Vitamin"
In a nonclinical elderly population, vitamin D supplementation had no significant effect on mood or other mental health outcomes.
Clozapine (Clozaril and others) is still the most efficacious antipsychotic drug when others offer little or no benefit. It also has special value in reducing suicidality and aggression, but, as Dr John Kane observed recently, this agent remains "strikingly underutilized."1