July 2011
Second-Generation Antipsychotics for Bipolar Maintenance Treatment
Second-generation antipsychotics are commonly used in maintenance treatment for bipolar disorder, but data supporting this use are very limited.
Dosing Lithium and Olanzapine for Bipolar Maintenance
A post hoc analysis of data from a study of maintenance treatments for bipolar disorder suggests optimal lithium levels for the prevention of manic or mixed episodes and optimal olanzapine doses to protect against depressive episodes.
Antipsychotic-Induced Constipation
Constipation is a common and sometimes severe adverse effect of antipsychotic treatment for patients with schizophrenia, and it occurs with both first- and second-generation agents.
Second-Generation Antipsychotics for Bipolar Maintenance Treatment
July 2011
A majority of antipsychotic drug prescriptions in the United States are now written for patients with bipolar disorder. All second-generation agents, except iloperidone (Fanapt), paliperidone (Invega), and clozapine (Clozaril and others), are labeled by the US Food and Drug Administration (FDA) for…

