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IN THIS ISSUE:
May 2011

Does LAIR Beat Oral Antipsychotics?
A study by Rosenheck et al failed to find long-acting injectable risperidone (Risperdal Consta) superior in efficacy to oral antipsychotics.

Healthy Diet/Healthy Heart/Healthy Brain?
People who eat more trans unsaturated fats may have an increased risk of depression.

In Brief
Prevalence of Eating Disorders in Adolescents; Gender Differences in Anxiety Disorders

Do Antidepressants Still Work?
From 1983 to 2008, the placebo-response rate in trials of antidepressants for major depressive disorder increased, while the effect size decreased.

Breast Cancer in Women with Schizophrenia: Approaches to Prevention
Compared with women in the general population, women with schizophrenia have even more risk factors for breast cancer, some of which are preventable.

Treatment-Resistant GAD: Little Evidence
For treatment-resistant generalized anxiety disorder, many treatment options have been tried, but few have been sufficiently studied.

Treatment-Resistant GAD: Little Evidence

May 2011

Six prescription drugs currently carry US Food and Drug Administration (FDA) labeling for generalized anxiety disorder (GAD). Four are antidepressants: the selective serotonin reuptake inhibitors (SSRIs) paroxetine (Paxil and others) and escitalopram (Lexapro) and the serotonin-norepinephrine reuptake…

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