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IN THIS ISSUE:
April 2011

Depression in Alzheimer Disease
Sertraline (Zoloft and others) offers little benefit for depression in patients with Alzheimer disease.

Do Beta-Blockers Cause Depression?
Propranolol (Inderal and others) and other lipid-soluble beta-blockers may cause depressive symptoms early in treatment.

Liquid Formulations of Psychotropics
Many psychotropic medications are available in liquid formulations, which increases clinical options.

L-theanine Augmentation for Schizophrenia
L-theanine augmentation is associated with modest improvement in schizophrenia symptoms.

Acupuncture for Depression?
A systematic evaluation of reviews of acupuncture for depression conclude that it is not superior to placebo.

In Brief
Deep brain stimulation treats hallucinations in patients with schizophrenia; Pimozide augmentation not effective for treatment-resistant schizophrenia

Second-Generation Antipsychotics for Depression and Anxiety
For both depression and anxiety, quetiapine (Seroquel) is efficacious as monotherapy and as an adjunct to antidepressants.

CME Reminder
Continuing Medical Education Assessment Questions are now due.

Acupuncture for Depression?

April 2011

Acupuncture is a "complementary and alternative" approach for treating depression. Ernst and coauthors systematically evaluated reviews on this subject via an electronic literature search, which included Korean and Chinese databases and was not limited by a particular time period or language.1

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