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IN THIS ISSUE:
February 2011

Lurasidone (Latuda)
The new antipsychotic lurasidone (Latuda) appears generally comparable in safety and efficacy to currently available agents.

Antipsychotics Increase the Risk of Venous Thromboembolism
Antipsychotics cause a small increase in the risk of venous thromboembolism in some patients.

Pramipexole for Cognitive Enhancement in Bipolar Disorder
In one study, adjunctive pramipexole (Mirapex and others) provided cognitive benefit for euthymic patients with bipolar disorder.

In Brief
Mindfulness-Based Cognitive Therapy Equivalent to Maintenance Antidepressant Treatment for Relapse Prevention; Docosahexaenoic Acid (DHA) Supplementation Does Not Slow Cognitive Decline in Patients with Alzheimer Disease

Anticonvulsants and Suicide Risk: The Saga Continues
A new study finds an increased risk of suicide in patients taking anticonvulsants for indications other than epilepsy but no additional risk in patients with epilepsy.

Pramipexole for Cognitive Enhancement in Bipolar Disorder

February 2011

Even when in affective remission, patients with bipolar disorder typically have significant cognitive impairment—persistent deficits in attention, verbal memory, and executive functions—that contributes substantially to disability.1 Studies of bipolar disorder treatments usually…

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