April 2010
Depression during Pregnancy
New guidelines aid clinicians in treating pregnant women with depression.
SSRIs versus an SNRI
A new study failed to find enhanced benefit from duloxetine (Cymbalta) compared with generic selective serotonin reuptake inhibitors in patients with depression.
Zopiclone and Morning-After Impairment
In a small trial of older adults, driving ability and cognitive performance were impaired the morning after subjects took a dose of zopiclone at bedtime.
In Brief
Antipsychotic Polypharmacy Does Not Increase Mortality Risk in Schizophrenia; Tarenflurbil Fails to Slow Cognitive Decline in Alzheimer’s Disease
Second-Generation Antipsychotics Cause Weight Gain and Adverse Metabolic Effects in Young Patients
Second-generation antipsychotics can be life-saving for youth with serious psychiatric illnesses, but they carry the risk for weight gain and possible long-term cardiovascular and metabolic problems.
In Brief
April 2010
As we discussed last December (BTP 2009;32:49-50), people with serious and chronic mental illness have a greater rate of mortality than the general population. A study by Tiihonen and others found that some antipsychotic medications increase excess mortality in patients with schizophrenia,…
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