April 2010
Depression during Pregnancy
New guidelines aid clinicians in treating pregnant women with depression.
SSRIs versus an SNRI
A new study failed to find enhanced benefit from duloxetine (Cymbalta) compared with generic selective serotonin reuptake inhibitors in patients with depression.
Zopiclone and Morning-After Impairment
In a small trial of older adults, driving ability and cognitive performance were impaired the morning after subjects took a dose of zopiclone at bedtime.
In Brief
Antipsychotic Polypharmacy Does Not Increase Mortality Risk in Schizophrenia; Tarenflurbil Fails to Slow Cognitive Decline in Alzheimer’s Disease
Second-Generation Antipsychotics Cause Weight Gain and Adverse Metabolic Effects in Young Patients
Second-generation antipsychotics can be life-saving for youth with serious psychiatric illnesses, but they carry the risk for weight gain and possible long-term cardiovascular and metabolic problems.
Depression during Pregnancy
April 2010
Approximately 10% to 20% of pregnant women suffer from depression. Between 1993 and 2003, the percentage of women treated with antidepressants during pregnancy increased from 5.7% to 13.4%.1 Use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy increases the risks of septal…

