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February 2010

Second-Generation Antipsychotics: New Information
Second-generation antipsychotics differ from each other, offering options for patients.

Cognitive Effects of Antipsychotic Drugs: Are All Created Equal?
First- and second-generation antipsychotics appear comparable in their ability to lessen cognitive dysfunction associated with schizophrenia.

In Brief
Long-acting Injectable Olanzapine Approved in US; High-potency Cannabis May Increase Risk of Psychosis

Olanzapine and Sertraline Combined for Psychotic Depression
In a short-term trial, sertraline (Zoloft and others) combined with olanzapine (Zyprexa) was more efficacious than olanzapine plus placebo for psychotic depression in both young and elderly patients.

In Brief

February 2010

The US Food and Drug Administration approved an extended-release injectable suspension preparation of olanzapine (Zyprexa Relprevv) on December 11, 2009, for the treatment of schizophrenia in adults. It is a long-acting atypical antipsychotic for deep intramuscular gluteal injection. We reviewed this…

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