Folate and Depression
L-methylfolate (Deplin) shows theoretical promise as an augmenting strategy for treatment-resistant depression, but so far there is little clinical evidence of its efficacy.
Lithium in Drinking Water May Decrease Suicide Risk; No Association Found Between Fish Consumption and Dementia
Breast Cancer, Tamoxifen, and 2D6 Inhibitors
Antidepressants and other drugs that inhibit the cytochrome P450 2D6 isoenzyme may cause low levels of tamoxifen in women with breast cancer.
Treating Depression in Parkinson's Disease
Two studies provide preliminary but encouraging data about nortriptyline and omega-3 fatty acids as potential treatments for depression in patients with Parkinson's disease.
Lithium appears to have an antisuicidal effect in people with mood disorders (BTP 2004;27:1-2). A 1990 study suggested that the presence of low levels of lithium in drinking water might have decreased the risk of suicide in Texas. A recent study has replicated these findings (Ohgami H, et al.…