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May 2009

Treating Fibromyalgia
Antidepressants offer some relief for sufferers of fibromyalgia.

Donepezil in Schizophrenia?
A recent report suggests donepezil (Aricept) does not appear to benefit cognitive symptoms of schizophrenia.

Second-Generation Antipsychotics and the Risk of Cardiac Death
Second-generation antipsychotics produce about the same level of cardiac risks as first-generation agents.

Preventing Dementia
Higher levels of education, mentally challenging work, and moderate coffee consumption may protect against Alzheimer’s disease, but Ginkgo biloba does not.

In Brief
Mixed Results for Modafinil as an Adjunct in Schizophrenia; Memantine Not Efficacious as an Adjunct in Schizophrenia

In Brief

May 2009

Approved by the US Food and Drug Administration to treat narcolepsy and shift work sleep disorder, modafinil (Provigil) is purported to have cognitive-enhancing effects in patients with schizophrenia, and it has been used off-label to treat antipsychotic-associated sedation in this population. Saavedra-Velez…

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