Subscribe to Biological Therapies in Psychiatry -  Choose your plan >
November 2008

Metformin for Antipsychotic-Associated Weight Gain
Most studies with metformin (Avandamet and others) suggest that it attentuates weight gain or actually promotes weight loss in patients who are taking antipsychotics.

In Brief
Valproate Teratogenicity Increased by High Dose, Concomitant Drugs;Celecoxib, Naproxen Do Not Protect Against Alzheimer's Disease

Atomoxetine versus Methylphenidate for Pediatric ADHD
Methylphenidate (Ritalin and others) appears to be more efficacious than atomoxetine (Strattera) for treating attention-deficit/hyperactivity disorder in children but has more adverse effects.

Rivastigmine (Exelon) Patch
A transdermal system for delivering rivastigmine (Exelon) is now available in the United States for treating dementia associated with Alzheimer's or Parkinson's disease.

In Brief

November 2008

Last June, we discussed the teratogenic potential of anticonvulsants in pregnant women with bipolar disorder (BTP 2008;31:22-23). A recent study suggests that if valproate (Depakote and others) must be used during pregnancy, it should be prescribed at the lowest dose possible and preferably…

To view the rest of this article, please: