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IN THIS ISSUE:
October 2008

Two Drugs for Fibromyalgia
Pregabalin (Lyrica) and duloxetine (Cymbalta) are approved in the United States for the treatment of fibromyalgia.

Preventing Poststroke Depression
In a 2008 study by Robinson and colleagues, escitalopram (Lexapro) and problem-solving therapy decreased the likelihood of poststroke depression.

Duloxetine for Elderly Patients with GAD
Due to possible adverse events, duloxetine (Cymbalta) should be a second-line option for elderly patients with generalized anxiety disorder.

In Brief
Switch to Aripiprazole Reduces Cardiovascular Risk in Schizophrenia; SSRIs Are Effective for Treating PMS/PMDD; Statins May Protect Against Dementia

Antidepressants for Social Anxiety Disorder
Sertraline (Zoloft and others), paroxetine (Paxil and others), venlafaxine (Effexor and others), and fluvoxamine (Luvox and others) appear to be the most efficacious antidepressants for the treatment of social anxiety disorder, with escitalopram (Lexapro) a reasonable alternative.

Preventing Poststroke Depression

October 2008

Over 700,000 Americans suffer a stroke each year.1 In combined studies of over 2000 patients, more than one-third of stroke survivors had an episode of depression within 2 years after the stroke.2 (The probability that a stroke victim will become depressed may be related to a…

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