March 2008
Topiramate for Alcohol Dependence
Topiramate (Topamax) has been found to be beneficial in treating alcohol dependence.
Early Intervention for Schizophrenia: A Role for Antidepressants?
Antidepressants may reduce the transition from a prodrome of pre-psychosis to schizophrenia in vulnerable individuals.
In Brief
Duloxetine Approved for GAD; Depression in Parkinson’s Disease; Asthma Linked to Psychiatric Disorder
Adjunctive Antipsychotics for MDD
Patients with treatment-resistant major depressive disorder may benefit from the addition of second-generation antipsychotics to an antidepressant medication regimen.
Antipsychotics in Youth with Schizophrenia
Early-onset schizophrenia-spectrum disorder requires long-term antipsychotic treatment, but children and adolescents are sensitive to antipsychotic side effects and should be monitored carefully.
Antipsychotics in Youth with Schizophrenia
March 2008
Only about 1% of adults with schizophrenia have a first onset of psychotic symptoms before age 13 years.1 The incidence then increases sharply between ages 12 and 14 years. As many as one-third of adults with schizophrenia have early-onset schizophrenia-spectrum (EOSS) disorder, defined…

