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IN THIS MONTH'S ISSUE:
February 2015

Bone Health in Older Patients: Effects of Depression and Antidepressants
Research suggests that depression contributes to bone thinning, but the effect of antidepressants on bone health is unclear.

Helping Smokers Quit
Combination treatment with varenicline (Chantix) and bupropion (Zyban) is more effective than varenicline alone in helping male smokers quit.

Lithium and Renal Tumors
Lithium-treated patients have a significantly greater incidence of renal cancer and benign renal tumors than patients not treated with lithium.

In Brief
FDA Adds Warning about Adverse Skin Reaction to Ziprasidone (Geodon) Labeling; Benzodiazepine Use in Elderly Is High Despite Concerns

QT Interval Prolonged in Schizophrenia
QT interval prolongation may be a manifestation of the biology of schizophrenia. Antipsychotics may cause additional prolongation.

Melatonin to Combat Olanzapine's Metabolic Effects?
Melatonin may help prevent the weight gain that often accompanies treatment with antipsychotic drugs.

A Message from Alan J. Gelenberg, M.D.

When I first started writing BTP in the 1970s, it was to bridge the gap between new knowledge in our field and its application to patient care. Over the decades since, the need for this bridge has become even greater. Neuroscience rockets forward. Psychiatrists and other clinicians have a broader array of treatments for patients with mental disorders than we even dreamed of back then. But we have less time to spend with patients and less time to keep up with developments that affect treatment decisions. Our medications, and those prescribed by colleagues in other specialties, are more varied, complex, and prone to interactions. What were formerly crisp boundaries between major psychopharmacologic categories are now murky.

This makes the modern practice of psychiatry challenging—but also fun and promising. With the expanding armamentarium of treatment options comes enhanced ability to alleviate suffering. The mission of BTP remains constant, even while the field grows. We are still here to bridge the gap, to make science applicable and relevant, and to help you in your day-to-day work relieve distress and improve function in patients' lives.