Generic Olanzapine: Switching from the Brand Name
Despite being associated with a significant drop in blood drug level, switching from brand name olanzapine to a generic formulation did not decrease clinical stability in one study.
Can Anticholinergics Increase Dementia Risk?
Some evidence suggests that, in elderly patients, anticholinergic medications appear to increase the risk of dementia.
The Mediterranean Diet and Cognition
A growing body of evidence suggests that interventions that support cardiovascular health, such as eating a "Mediterranean" type of diet, can also benefit the brain.
Asenapine (Saphris): Once vs Twice Daily
Taking asenapine once rather than twice a day might help offset daytime sleepiness.
Patients with Schizophrenia Who Have High Cholesterol Levels Score Better on Cognitive Tests; Supplementation with Folic Acid and Vitamin B Does Not Reduce Depression Risk in Older Women
The new hypnotic drug suvorexant, approved for the treatment of insomnia, appears to be similar to earlier agents in terms of effectiveness and side effects, including next-day problems with motor skills, alertness, and cognition.
A Message from Alan J. Gelenberg, M.D.
When I first started writing BTP in the 1970s, it was to bridge the gap between new knowledge in our field and its application to patient care. Over the decades since, the need for this bridge has become even greater. Neuroscience rockets forward. Psychiatrists and other clinicians have a broader array of treatments for patients with mental disorders than we even dreamed of back then. But we have less time to spend with patients and less time to keep up with developments that affect treatment decisions. Our medications, and those prescribed by colleagues in other specialties, are more varied, complex, and prone to interactions. What were formerly crisp boundaries between major psychopharmacologic categories are now murky.
This makes the modern practice of psychiatry challenging—but also fun and promising. With the expanding armamentarium of treatment options comes enhanced ability to alleviate suffering. The mission of BTP remains constant, even while the field grows. We are still here to bridge the gap, to make science applicable and relevant, and to help you in your day-to-day work relieve distress and improve function in patients' lives.