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IN THIS MONTH'S ISSUE:
May 2015

Intranasal Ketamine for MDD
An intranasal application of ketamine could be an easier and more practical means to deliver this rapid-acting agent for patients with major depressive disorder.

Smoking and Erectile Dysfunction
A meta-analysis found a positive dose-response association between both the quantity and duration of smoking and the risk that a patient developed erectile dysfunction.

Statins and Depression Risk
Results from a study of statin use in patients with depression support other evidence that this widely used class of drugs may protect brain health.

A Single Elevated Lithium Level Can Impact Renal Function
In almost 700 lithium-treated patients, a single lithium level greater than 1.0 mmol/L was associated with a significant decrease in estimated glomerular filtration rate (eGFR) for at 3 months.

In Brief
FDA Cautions Against Using Testosterone Products for Low Testosterone Levels Due to Aging; Weight Loss Supplement Contains Hidden Fluoxetine

Antipsychotics in PTSD
Many veterans are treated off-label with antipsychotics for post-traumatic stress disorder (PTSD) despite a lack of evidence for their efficacy.

About the Editorial Advisory Committee

Editorial Advisory Committee:
Ross J. Baldessarini, M.D.
Joseph Biederman, M.D.
Rubin Bressler, M.D.
Andrew W. Brotman, M.D.
Ned Cassem, M.D.
Harold J. DeMonaco, M.S., R.Ph.
Susan R. Donaldson, M.D.
William E. Falk, M.D.
John Greist, M.D.
James W. Jefferson, M.D.
David Katzelnick, M.D.
Samuel J. Keith, M.D.
Martin B. Keller, M.D.
John Racy, M.D.
Eric M. Reiman, M.D.
Jerrold F. Rosenbaum, M.D.
A. John Rush, M.D.
Alan F. Schatzberg, M.D.
Nina R. Schooler, Ph.D.
Michael E. Thase, M.D.
Joanne Doller Wojcik, R.N., M.S.

Editor
Alan J. Gelenberg, M.D.

Assistant Editor
Heather S. Hopkins

Managing Editor
Amy Boynton