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IN THIS MONTH'S ISSUE:
February 2015

Bone Health in Older Patients: Effects of Depression and Antidepressants
Research suggests that depression contributes to bone thinning, but the effect of antidepressants on bone health is unclear.

Helping Smokers Quit
Combination treatment with varenicline (Chantix) and bupropion (Zyban) is more effective than varenicline alone in helping male smokers quit.

Lithium and Renal Tumors
Lithium-treated patients have a significantly greater incidence of renal cancer and benign renal tumors than patients not treated with lithium.

In Brief
FDA Adds Warning about Adverse Skin Reaction to Ziprasidone (Geodon) Labeling; Benzodiazepine Use in Elderly Is High Despite Concerns

QT Interval Prolonged in Schizophrenia
QT interval prolongation may be a manifestation of the biology of schizophrenia. Antipsychotics may cause additional prolongation.

Melatonin to Combat Olanzapine's Metabolic Effects?
Melatonin may help prevent the weight gain that often accompanies treatment with antipsychotic drugs.

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Originating at the Massachusetts General Hospital and Harvard Medical School, Biological Therapies in Psychiatry has been a trusted resource for physicians for over 30 years. Described as "influential" by the Atlantic Monthly, this concise, four-page, monthly newsletter provides up-to-date information about the rapidly expanding field of psychotropic medications and other biological treatments for mental disorders.

From his perspective as an editor, teacher, investigator, and clinician, Alan J. Gelenberg, M.D., reviews the widespread literatures of science and clinical practice. Dr. Gelenberg distills the material most relevant for a busy practitioner and presents it each month with a balance of scientific curiosity, healthy skepticism, and clinical experience.

Dr. Gelenberg is Professor and Interim Chair of Psychiatry at Penn State, Hershey. Since 1987, Dr. Gelenberg has been Editor-in-Chief of the Journal of Clinical Psychiatry, and he recently chaired the workgroup that revised the American Psychiatric Association's major depressive disorder guidelines. Dr. Gelenberg has been on the faculty of Harvard Medical School, MIT, and the University of Arizona and has written numerous scientific articles and book chapters on mood disorders, depression, and schizophrenia. He is listed in the Best Doctors in America and America's Top Doctors and received the 1997 Exemplary Psychiatrist Award of the National Alliance for the Mentally Ill.

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