May 2013
Iloperidone Increases QTc
Coadministration of drugs that inhibit cytochrome P450 2D6 or 3A4 increases the potential for iloperidone (Fanapt) to prolong the QTc interval.
Diabetes and Dyslipidemia: Risks for Adolescents with Mental Illness
A retrospective cohort study found that adolescents with schizophrenia or bipolar disorder had higher rates of both diabetes and dyslipidemia.
Memantine for FTD: A Negative Study
In a double-blind, parallel-group study, memantine (Namenda) produced no benefit greater than placebo for patients with frontotemporal dementia but more frequent cognitive adverse events.
Inappropriate Sexual Behavior in FTD: A Case Report
Aripiprazole (Abilify) reduced inappropriate sexual behavior in an elderly man with frontotemporal dementia.
In Brief
Age and Dose Play a Role in the Effects of Antidepressants on Fracture Risk; Weight Management Intervention Program Beneficial for Patients with Schizophrenia
Hypertension following SSRI Withdrawal
A woman with depression experienced hypertension when citalopram (Celexa and others) was abruptly discontinued.
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Originating at the Massachusetts General Hospital and Harvard Medical School, Biological Therapies in Psychiatry has been a trusted resource for physicians for over 30 years. Described as "influential" by the Atlantic Monthly, this concise, four-page, monthly newsletter provides up-to-date information about the rapidly expanding field of psychotropic medications and other biological treatments for mental disorders.
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Dr. Gelenberg is Professor and Interim Chair of Psychiatry at Penn State, Hershey. Since 1987, Dr. Gelenberg has been Editor-in-Chief of the Journal of Clinical Psychiatry, and he recently chaired the workgroup that revised the American Psychiatric Association's major depressive disorder guidelines. Dr. Gelenberg has been on the faculty of Harvard Medical School, MIT, and the University of Arizona and has written numerous scientific articles and book chapters on mood disorders, depression, and schizophrenia. He is listed in the Best Doctors in America and America's Top Doctors and received the 1997 Exemplary Psychiatrist Award of the National Alliance for the Mentally Ill.
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