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IN THIS MONTH'S ISSUE:
April 2017

Anticytokine Treatment for Depression?
Preliminary evidence supports further study of anticytokines for treating depression.

Antidepressants and Fetal Malformations
The overall increase in risk to the fetus from antidepressant exposure during pregnancy is relatively low.

Sleep Medication in Depressed Adolescents
Depressed adolescents who receive trazodone (Desyrel and others) in addition to antidepressants or cognitive-behavioral therapy (CBT) may have worse depression response and increased self-harm.

In Brief
Central Nervous System Polypharmacy Has Increased for Elderly Patients in Outpatient Care Settings; Prolactin-Elevating Antipsychotics Do Not Increase the Risk of Endometrial Cancer

Lithium in Drinking Water: Effects on Adolescents
In a cross-sectional study of junior high students, lithium levels in tap water were inversely correlated with depressive symptoms and interpersonal violence but not with suicidal behaviors.

Diet and Depression: More Data
In a small randomized, controlled trial, the addition of dietary support to psychotherapy or medication treatment for depressed adults was associated with significantly greater improvement in depression scores than the addition of social support.

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Originating at the Massachusetts General Hospital and Harvard Medical School, Biological Therapies in Psychiatry has been a trusted resource for physicians for over 30 years. Described as "influential" by the Atlantic Monthly, this concise, four-page, monthly newsletter provides up-to-date information about the rapidly expanding field of psychotropic medications and other biological treatments for mental disorders.

From his perspective as an editor, teacher, investigator, and clinician, Alan J. Gelenberg, M.D., reviews the widespread literatures of science and clinical practice. Dr. Gelenberg distills the material most relevant for a busy practitioner and presents it each month with a balance of scientific curiosity, healthy skepticism, and clinical experience.

Dr. Gelenberg is Professor and Interim Chair of Psychiatry at Penn State, Hershey. Since 1987, Dr. Gelenberg has been Editor-in-Chief of the Journal of Clinical Psychiatry, and he recently chaired the workgroup that revised the American Psychiatric Association's major depressive disorder guidelines. Dr. Gelenberg has been on the faculty of Harvard Medical School, MIT, and the University of Arizona and has written numerous scientific articles and book chapters on mood disorders, depression, and schizophrenia. He is listed in the Best Doctors in America and America's Top Doctors and received the 1997 Exemplary Psychiatrist Award of the National Alliance for the Mentally Ill.

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