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IN THIS MONTH'S ISSUE:
November 2014

Adjunctive Atorvastatin (Lipitor) for MDD?
In a study of patients with major depressive disorder (MDD), adding atorvastatin (Lipitor) to citalopram (Celexa and others) treatment was associated with lower scores on the Hamilton Depression Rating Scale (HDRS).

Antidepressants, Pregnancy, and the Risk of Cardiac Defects
A large cohort study found that commonly prescribed antidepressant medications do not appear to carry cardiac teratogenic effects when used during pregnancy.

Psychotropics and Suicide
FDA warnings that antidepressants and atomoxetine (Strattera) could increase suicidal thinking impacted prescribing patterns and the incidence of psychotropic drug poisonings.

In Brief
Exposure to SSRIs Does Not Increase Risk of Hepatocellular Carcinoma in Patients with Hepatitis C Infection; Hyperconnectivity Exists Between Brain Networks in Young Unmedicated Remitted Patients with Depression

Antipsychotic Dose Reduction and Adverse Effects
A study of patients with schizophrenia found that decreasing the dose of risperidone (Risperdal and others) or olanzapine (Zyprexa and others) by half did not affect the rate of adverse metabolic effects.

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Originating at the Massachusetts General Hospital and Harvard Medical School, Biological Therapies in Psychiatry has been a trusted resource for physicians for over 30 years. Described as "influential" by the Atlantic Monthly, this concise, four-page, monthly newsletter provides up-to-date information about the rapidly expanding field of psychotropic medications and other biological treatments for mental disorders.

From his perspective as an editor, teacher, investigator, and clinician, Alan J. Gelenberg, M.D., reviews the widespread literatures of science and clinical practice. Dr. Gelenberg distills the material most relevant for a busy practitioner and presents it each month with a balance of scientific curiosity, healthy skepticism, and clinical experience.

Dr. Gelenberg is Professor and Interim Chair of Psychiatry at Penn State, Hershey. Since 1987, Dr. Gelenberg has been Editor-in-Chief of the Journal of Clinical Psychiatry, and he recently chaired the workgroup that revised the American Psychiatric Association's major depressive disorder guidelines. Dr. Gelenberg has been on the faculty of Harvard Medical School, MIT, and the University of Arizona and has written numerous scientific articles and book chapters on mood disorders, depression, and schizophrenia. He is listed in the Best Doctors in America and America's Top Doctors and received the 1997 Exemplary Psychiatrist Award of the National Alliance for the Mentally Ill.

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