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IN THIS MONTH'S ISSUE:
May 2015

Intranasal Ketamine for MDD
An intranasal application of ketamine could be an easier and more practical means to deliver this rapid-acting agent for patients with major depressive disorder.

Smoking and Erectile Dysfunction
A meta-analysis found a positive dose-response association between both the quantity and duration of smoking and the risk that a patient developed erectile dysfunction.

Statins and Depression Risk
Results from a study of statin use in patients with depression support other evidence that this widely used class of drugs may protect brain health.

A Single Elevated Lithium Level Can Impact Renal Function
In almost 700 lithium-treated patients, a single lithium level greater than 1.0 mmol/L was associated with a significant decrease in estimated glomerular filtration rate (eGFR) for at 3 months.

In Brief
FDA Cautions Against Using Testosterone Products for Low Testosterone Levels Due to Aging; Weight Loss Supplement Contains Hidden Fluoxetine

Antipsychotics in PTSD
Many veterans are treated off-label with antipsychotics for post-traumatic stress disorder (PTSD) despite a lack of evidence for their efficacy.

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Originating at the Massachusetts General Hospital and Harvard Medical School, Biological Therapies in Psychiatry has been a trusted resource for physicians for over 30 years. Described as "influential" by the Atlantic Monthly, this concise, four-page, monthly newsletter provides up-to-date information about the rapidly expanding field of psychotropic medications and other biological treatments for mental disorders.

From his perspective as an editor, teacher, investigator, and clinician, Alan J. Gelenberg, M.D., reviews the widespread literatures of science and clinical practice. Dr. Gelenberg distills the material most relevant for a busy practitioner and presents it each month with a balance of scientific curiosity, healthy skepticism, and clinical experience.

Dr. Gelenberg is Professor and Interim Chair of Psychiatry at Penn State, Hershey. Since 1987, Dr. Gelenberg has been Editor-in-Chief of the Journal of Clinical Psychiatry, and he recently chaired the workgroup that revised the American Psychiatric Association's major depressive disorder guidelines. Dr. Gelenberg has been on the faculty of Harvard Medical School, MIT, and the University of Arizona and has written numerous scientific articles and book chapters on mood disorders, depression, and schizophrenia. He is listed in the Best Doctors in America and America's Top Doctors and received the 1997 Exemplary Psychiatrist Award of the National Alliance for the Mentally Ill.

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