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IN THIS MONTH'S ISSUE:
April 2014

Zinc and Depression
Preliminary evidence suggests that zinc deficiency may be associated with depression.

Antidepressant-Induced Sexual Dysfunction: Exercise as an Antidote?
In women experiencing antidepressant-induced sexual dysfunction, exercise appears to improve sexual desire, global sexual function, and orgasm function.

Varenicline in Patients with Depression History
In a study of subjects with past or current depression, varenicline (Chantix) improved cigarette smoking abstinence rates without producing neuropsychiatric adverse effects.

Fluoxetine and the QTc Interval
QTc prolongation can occur in association with fluoxetine (Prozac and others) in patients with a personal or family history of the condition or predisposing risk factors, and in those taking certain other medications.

In Brief
Auditory Training via Computers Improves Cognitive Function in Schizophrenia; Salivary Cortisol Levels Predict Risk for Depression in Young Males

Antipsychotic Strategies in First-Episode Schizophrenia
A recent study found little benefit for high-dose antipsychotic treatment in patients with a first episode of schizophrenia who were nonresponsive to recommended doses.

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Originating at the Massachusetts General Hospital and Harvard Medical School, Biological Therapies in Psychiatry has been a trusted resource for physicians for over 30 years. Described as "influential" by the Atlantic Monthly, this concise, four-page, monthly newsletter provides up-to-date information about the rapidly expanding field of psychotropic medications and other biological treatments for mental disorders.

From his perspective as an editor, teacher, investigator, and clinician, Alan J. Gelenberg, M.D., reviews the widespread literatures of science and clinical practice. Dr. Gelenberg distills the material most relevant for a busy practitioner and presents it each month with a balance of scientific curiosity, healthy skepticism, and clinical experience.

Dr. Gelenberg is Professor and Interim Chair of Psychiatry at Penn State, Hershey. Since 1987, Dr. Gelenberg has been Editor-in-Chief of the Journal of Clinical Psychiatry, and he recently chaired the workgroup that revised the American Psychiatric Association's major depressive disorder guidelines. Dr. Gelenberg has been on the faculty of Harvard Medical School, MIT, and the University of Arizona and has written numerous scientific articles and book chapters on mood disorders, depression, and schizophrenia. He is listed in the Best Doctors in America and America's Top Doctors and received the 1997 Exemplary Psychiatrist Award of the National Alliance for the Mentally Ill.

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